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Recombinant Human PKC iota (N-GST tag)

Recombinant Human PKC iota (N-GST tag)

Catalog Number:
E001278515APP
Mfr. No.:
Z500317
Price:
$496
  • Size:
    10 µg
    Quantity:
    Add to Cart:
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      • Overview

        • PKC? is a member of the protein kinase C family of serine-threonine kinases. The amino acid sequence of PKC? showed greatest homology to PKCzeta, with 72% identity overall rising to 84% in the catalytic domain. Protein kinase C iota (PKC?) has been implicated in Ras signaling and is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively active PKC? in the colon are highly susceptible to carcinogen-induced colon carcinogenesis.

          Please contact us at for specific academic pricing.

      • Properties
        • Name
          PRKCI; DXS1179E; MGC26534; nPKC-iota
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          98.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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