Recombinant Human PKAc alpha (N-GST tag)

Recombinant Human PKAc alpha (N-GST tag)

Catalog Number:
E001278505APP
Mfr. No.:
Z500307
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • The catalytic subunit C-alpha of PKA (PKAca) is a member of the Ser/Thr protein kinase family and has been assigned to chromosome region 19p13.1. Null mutation in PKAca leads to early postnatal lethality in the majority of C-alpha knockout mice. Surprisingly, a small percentage of C-alpha knockout mice, although runted, survived to adulthood. In these animals, compensatory increases in C-beta levels occurred in brain whereas many tissues, including skeletal muscle, heart, and sperm, contained less than 10% of the normal PKA activity.

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      • Properties
        • Name
          PKAa; cAPKa; MGC48865; MGC102831
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          69.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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