Recombinant Human PI3K (p120 gamma) (N-His tag)

Recombinant Human PI3K (p120 gamma) (N-His tag)

Catalog Number:
E001278500APP
Mfr. No.:
Z500293
Price:
$768
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • PI3K (p120γ) is a member of the PI3K family that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. PI3K (p120γ) is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, PI3K (p120γ) is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. In addition, PI3K (p120γ) plays an inhibitory role in inflammatory mediator-induced human vascular smooth muscle cell calcification through regulating alkaline phosphatase expression.

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      • Properties
        • Name
          p110γ: PI3K, PIK3, PI3CG, PI3Kgamma
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          121.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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