Name: Recombinant Human PDZ Domain Containing 1
Price: Inquiry

- Overview
  - PDZK1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 542 amino acids (1-519 a.a.) and having a molecular mass of 59.0kDa. PDZK1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PDZK1 is a PDZ domain-containing scaffolding protein which facilitates localization of cell surface proteins and has a key part in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphism in this gene is linked to metabolic syndrome, and overexpression results in drug resistance of multiple myeloma.
    
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- Properties
  - Protein Name
    
    PDZ Domain Containing 1, PDZ-Containing Kidney Protein 1, Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF3, Na/Pi Cotransporter C-Terminal-Associated Protein 1, Sodium-Hydrogen Exchanger Regulatory Factor 3, CFTR-Associated Protein Of 70 KDa, NHERF-3
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90% as determined by SDS-PAGE.
    
    Formulation
    
    PDZK1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.1M NaCl, 0% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human PDZ Domain Containing 1

Recombinant Human PDZ Domain Containing 1

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