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Recombinant human PD-1 protein with C-terminal human Fc and 6×His tag

Recombinant human PD-1 protein with C-terminal human Fc and 6×His tag

Catalog Number:
P001418064ABE
Mfr. No.:
Abe32-17076
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      • Overview

        • The protein has a predicted molecular mass of 42.9 kDa after removal of the signal peptide. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

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      • Properties
        • Protein Name
          PDCD1, PD1, CD279, SLEB2
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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