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Recombinant human NTB-A protein with C-terminal mouse Fc and 6×His tag

Recombinant human NTB-A protein with C-terminal mouse Fc and 6×His tag

Catalog Number:
P001418028ABE
Mfr. No.:
Abe32-17048
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      • Overview

        • The protein has a predicted molecular mass of 50.1 kDa after removal of the signal peptide. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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      • Properties
        • Protein Name
          NTB-A, SLAMF6, Ly108, NK-T-B-antigen, CD352, KALI
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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