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Overview
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The protein has a predicted molecular mass of 75.7 kDa after removal of the signal peptide. The apparent molecular mass of ICAM-1-mFc is approximately 90-120 kDa due to glycosylation. This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
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- Properties
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Overview