Recombinant Human Non-T-cell Activation Linker

Recombinant Human Non-T-cell Activation Linker

Catalog Number:
P001413594ABE
Mfr. No.:
Abe32-4349
Price:
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • NTAL Human Recombinant produced in E. Coli is a single, non-glycosylated,polypeptide chain containing 238 amino acids (27-243 a.a.) and having a molecular mass of 26.2 kDa. NTAL protein is fused to a 21 amino acid His tag at N-terminus and is purified by standard chromatography. NTAL participates in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. NTAL takes part in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

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      • Properties
        • Protein Name
          LAT2, Linker for Activation of T CellsFamily Member 2, HSPC046, LAB, WBSCR15, WBSCR5, WSCR5, Non-T-cell activation linker, Linker for activation of B-cells, Membrane-associated adapter molecule, Williams-Beuren syndrome chromosomal region 5 protein
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 80% as determined by SDS-PAGE.
          Formulation
          NTAL Human solution containing 20mM Trsi HCL pH-8, & 10% glycerol.
          Storage
          NTAL Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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