Recombinant Human Natural Cytotoxicity Triggering Receptor 3

Recombinant Human Natural Cytotoxicity Triggering Receptor 3

Catalog Number:
P001413544ABE
Mfr. No.:
Abe32-4299
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • NCR3 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids (19-138 a.a) and having a molecular mass of 15.3kDa. NCR3 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cytotoxicity Triggering Receptor 3 also known as NCR3 is a natural cytotoxicity receptor (NCR) which assists NK cells in the lysis of tumor cells. Moreover, NCR3 interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of NCR3 has been related with mild malaria suceptibility. Three transcript variants encoding various isoforms have been found for this gene.

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      • Properties
        • Protein Name
          Natural Cytotoxicity Triggering Receptor 3, LY117, 1C7, LymphocyteAntigen 117, Activating Natural Killer Receptor P30, Natural Killer CellP30-Related Protein, NK-p30, NKp30, CD337, MALS, Activating NK-A1 Receptor, CD337Antigen, NKP30.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greaterthan 90% as determined by SDS-PAGE.
          Formulation
          NCR3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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