Name: Recombinant Human MYC Induced Nuclear Antigen
Price: Inquiry

- Overview
  - MINA Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 485 amino acids (1-465 a.a) andhaving a molecular mass of 54.9kDa. MINA is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. MYC Induced Nuclear Antigen, also known as MINA is an oxygenase whichcan function both as a histone lysine demethylase and a ribosomal histidine hydroxylase. MINA is involved in the demethylation of trimethylatedLys-9 on histone H3 (H3K9me3), leading to an increase in ribosomal RNAexpression. MINA also catalyzes thehydroxylation of 60S ribosomal protein L27a on His-39. In addition, MINA plays a significant role in cell growth andsurvival. MINA is implicated in ribosomebiogenesis, probably in the duration of the assembly process of pre-ribosomalparticles.
    
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- Properties
  - Protein Name
    
    MYC Induced Nuclear Antigen, MINA53, MDIG, 60S RibosomalProtein L27a Histidine Hydroxylase, Mineral Dust-Induced Gene Protein, HistoneLysine Demethylase MINA Ribosomal Oxygenase MINA, Nucleolar Protein 52, NO52, ROX, Bifunctional Lysine-Specific
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    MINA protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human MYC Induced Nuclear Antigen

Recombinant Human MYC Induced Nuclear Antigen

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