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Recombinant human MSLN(296-580) protein with C-terminal mouse Fc and 6×His tag

Recombinant human MSLN(296-580) protein with C-terminal mouse Fc and 6×His tag

Catalog Number:
P001418009ABE
Mfr. No.:
Abe32-17031
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      • Overview

        • The protein has a predicted molecular mass of 59.3 kDa after removal of the signal peptide. This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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      • Properties
        • Protein Name
          MSLN, Mesothelin, MPF
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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