Name: Recombinant human IL6 protein with C-terminal mouse Fc and 6×His tag
Price: Inquiry

- Overview
  - The protein has a predicted molecular mass of 47.9 kDa after removal of the signal peptide. This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
    
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- Properties
  - Protein Name
    
    IL6, Interleukin-6, BSF2, HSF, IFNB2
    
    Source
    
    HEK293 cells
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
    
    Formulation
    
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    
    Storage
    
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human IL6 Protein, mFc-His Tag on SDS-PAGE under reducing condition.

Recombinant human IL6 protein with C-terminal mouse Fc and 6×His tag

Recombinant human IL6 protein with C-terminal mouse Fc and 6×His tag

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