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Recombinant Human MLK4 (N-GST tag)

Recombinant Human MLK4 (N-GST tag)

Catalog Number:
E001278443APP
Mfr. No.:
Z500230
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
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      • Overview

        • MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains. The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions. MLK4 is highly expressed in kidney and pancreas. MLK4 is a negative regulator of TLR4.

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      • Properties
        • Name
          dJ862P8.3; KIAA1804; RP5-862P8.2
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          61.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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