Recombinant Human Mitochondrial Antiviral Signaling Protein

Recombinant Human Mitochondrial Antiviral Signaling Protein

Catalog Number:
P001413428ABE
Mfr. No.:
Abe32-4177
Price:
  • Size:
    5 µg
    Quantity:
    Add to Cart:
      • Overview
        • MAVS Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 536 amino acids (1-513) and having a molecular mass of 55.9 kDa. MAVS is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mitochondrial antiviral signaling protein (MAVS) is vital for innate immune defense against viruses. MAVS is an intermediary protein essential in the virus-triggered beta interferon signaling pathways. MAVS is involved in activation of transcription factors that regulate expression of beta interferon and contributes to antiviral immunity.

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      • Properties
        • Protein Name
          CARDIF, IPS-1, IPS1, VISA, Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Interferon beta promoter stimulator protein 1, Putative NF-kappa-B-activating protein 031N, Virus-induced-signaling adapter, KIAA1271.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85% as determined by SDS-PAGE.
          Formulation
          The MAVS solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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