Name: Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 2
Price: Inquiry

- Overview
  - MAPRE2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 347 amino acids (1-327 a.a.) and having a molecular mass of 39.2kDa. MAPRE2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. MAPRE2 (RP1 or EB2) is an evolutionarily conserved protein, which associates with the tips of growing microtubules, and regulates microtubule dynamics and their interactions with intracellular structures. The EB proteins regulate microtubule function through CLIP proteins. MAPRE2 shares noteworthy homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. MAPRE2 is necessary for spindle symmetry during mitosis. MAPRE2 is believed to have a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells.
    
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- Properties
  - Protein Name
    
    Microtubule-associated protein RP/EB family member 2, APC-binding protein EB2, End-binding protein 2, EB2, MAPRE2, RP1, EB1.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85% as determined by SDS-PAGE.
    
    Formulation
    
    MAPRE2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 2

Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 2

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