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Overview
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MESDC2 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (34-234 a.a.) and having a molecular mass of 24.9kDa (Molecular weight on SDS-PAGE will appear higher). The MESDC2 is purified by proprietary chromatographic techniques. Mesoderm development candidate 2 (MESDC2) is required for formation of the primitive streak and mesoderm during embryogenesis. MESDC2 binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression.
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- Properties
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Overview