Name: Recombinant Human Mesoderm Development Candidate 1
Price: Inquiry

- Overview
  - MESDC1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids (1-362) and having a molecular mass of 40.1 kDa. MESDC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mesoderm development candidate 1 (MESDC1) is a member of the MESD family. MESDC1 is a 362 amino acid protein encoded by a gene which maps to human chromosome 15q25.1. MESDC1 serves as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and specifically associates with Wnt signaling pathway coreceptors LRP5 and LPR6. MESDC1 is needed for proper LRP5/6 folding and maturation to the cell surface, which has a key role in Wnt signaling.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Mesoderm Development Candidate 1, MESDC1.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95.0% as determined by SDS-PAGE.
    
    Formulation
    
    The MESDC1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Mesoderm Development Candidate 1

Recombinant Human Mesoderm Development Candidate 1

We Also Recommend

Recombinant Human Mesoderm Development Candidate 2

Recombinant Human Microfibrillar-associated Protein 2

Recombinant Human Microfibrillar-associated Protein 3