Name: Recombinant Human LSM5 Homolog, U6 Small Nuclear RNA Associated
Price: Inquiry

- Overview
  - LSM5 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (1-91 a.a) and having a molecular mass of 12.3kDa. LSM5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. LSM5also known as LSM5 Homolog, U6 Small Nuclear RNA Associated belongs to the Smprotein family. This family is identified in a variety of organismsbased on sequence homology. Sm-like proteins contain the Sm sequence motif,which consists of 2 regions separated by a linker of variable length whichfolds as a loop. In addition, the Sm-like proteins are thought to create astable heteromer present in tri-snRNPparticles, which are important for pre-mRNA splicing. Among the diseasesassociated with LSM5 are spinal muscular atrophy, and muscular atrophy.
    
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- Properties
  - Protein Name
    
    LSM5 homolog, U6 small nuclear RNA associated(S.cerevisiae), YER146W, U6 snRNA-associated Sm-like protein LSm5.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95.0% as determined by SDS-PAGE.
    
    Formulation
    
    LSM5 protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.5), 10% glycerol, 0.15M NaCl and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human LSM5 Homolog, U6 Small Nuclear RNA Associated

Recombinant Human LSM5 Homolog, U6 Small Nuclear RNA Associated

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