Recombinant Human Left-Right Determination Factor 2

Recombinant Human Left-Right Determination Factor 2

Catalog Number:
P001413357ABE
Mfr. No.:
Abe32-4107
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • CD47 HumanRecombinant produced in Sf9 Insect cell is a single, non-glycosylated polypeptide chain containing 362 amino acids (19-141aa.a) and having a molecular mass of 40.9kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions). CD47 is fused to a 239 amino acid hIgG-His-tag at C-terminus & purified by proprietary chromatographic techniques. CD47, functions in cell adhesions by performing as an adhesion receptor for THBS1 on platelets, furthermore CD47 plays a role in the modulation of integrins. In addition, CD47 takes a vital part in memory formation as well as synaptic plasticity in the hippocampus. Receptor for SIRPA avoids maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 prevents premature elimination of red blood cells, and it is also implicated in membrane permeability changes induced following virus infection.

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      • Properties
        • Protein Name
          CD47Molecule, Antigenic Surface Determinant Protein OA3, CD47 Antigen (Rh-RelatedAntigen, Integrin-Associated Signal Transducer), Antigen Identified byMonoclonal, Antibody 1D8, Integrin Associated Protein, Integrin-AssociatedProtein, Rh-Related
          Source
          Sf9 cells
          Type
          Recombinant Proteins
          Purification
          Greater than 95.0% as determined by SDS-PAGE.
          Formulation
          CD47 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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