Recombinant Human Killer Cell Lectin-Like Receptor Subfamily C, Member 2

Recombinant Human Killer Cell Lectin-Like Receptor Subfamily C, Member 2

Catalog Number:
P001413315ABE
Mfr. No.:
Abe32-4061
Price:
  • Size:
    10 µg
    Quantity:
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      • Overview
        • KLRC2 Human Recombinant produced in E. coli is a single polypeptide chain containing 183 amino acids (94-231) and having a molecular mass of 18.4 kDa. KLRC2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. KLRC2 has a part as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed mainly in natural killer (NK) cells and encodes a family of transmembrane proteins categorized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is situated inside the NK complex, a region which holds a few C-type lectin genes specially expressed on NK cells. KLRC2 alternative splice variants are known but their full-length nature is yet to be determined.

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      • Properties
        • Protein Name
          Killer cell lectin-like receptor subfamily C member 2, NKG2-C type II integral membrane protein, NKG2-C-activating NK receptor, CD159 antigen-like family member C, NK cell receptor C, NKG2C, CD159c.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85% as determined by SDS-PAGE.
          Formulation
          The KLRC2 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 4M urea and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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