Name: Recombinant Human KCNMB3
Price: Inquiry

- Overview
  - KCNMB3 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 149 amino acids (82-207 a.a) andhaving a molecular mass of 16.8kDa. KCNMB3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. The KCNMB3 belongs to a family of 4 auxiliary beta subunits found in the mammalian genome, which associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene is comprised of 4 N-terminal alternative exons which produce 4 functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, display kinetically distinct inactivation behaviors.
    
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- Properties
  - Protein Name
    
    Potassium Channel Subfamily M Regulatory Beta Subunit 3, PotassiumLarge Conductance Calcium-Activated Channel, Subfamily M Beta Member 3, Calcium-ActivatedPotassium Channel, Subfamily M Subunit Beta-3, Charybdotoxin Receptor SubunitBeta-3, Big Pot
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    KCNMB3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human KCNMB3

Recombinant Human KCNMB3

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