Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (C-8His)

Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (C-8His)

Catalog Number:
P001412466ABE
Mfr. No.:
Abe32-8688
Price:
  • Size:
    Quantity:
    Add to Cart:
      • Overview
        • MW : 48.1kD. Recombinant Human Isocitrate Dehydrogenase is produced by our E.coli expression system and the target gene encoding Met1-Leu414 is expressed with a 8His tag at the C-terminus. Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the a-hydroxylation of phytanic acid.

          Please contact us at for specific academic pricing.

      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 50mM Tris, 200mM NaCl, 10% glycerol, pH8.0.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          3417

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    Copyright © Amerigo Scientific. All rights reserved.