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Recombinant human IL10R protein with C-terminal human Fc tag

Recombinant human IL10R protein with C-terminal human Fc tag

Catalog Number:
P001417239ABE
Mfr. No.:
Abe32-17239
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      • Overview

        • The protein has a predicted molecular mass of 49.06 kDa after removal of the signal peptide. The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

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      • Properties
        • Protein Name
          CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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