Name: Recombinant Human IL-1 RAcP/IL-1 R3 (C-Fc-6His)
Price: Inquiry

- Overview
  - MW : 66.7kD. Recombinant Human Interleukin-1 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Ser21-Gln356 is expressed with a Fc, 6His tag at the C-terminus. IL-1 Receptor Accessory Protein (IL-1 RAcP,IL-1 R3) is a ubiquitously expressed 70 - 90 kDa member of the interleukin-1 receptor family of proteins. It is mostly expressed in liver, skin, placenta, thymus and lung. Mature human IL-1 RAcP is a type I transmembrane glycoprotein that is 550 amino acids (aa) in length. It contains a 347 aa extracellular region (aa 21 - 367), a 21 aa transmembrane segment, and a 182 aa cytoplasmic domain. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. It is a subunit of the functional signaling complex with IL-1 RI and associates with IL-1 RII in a non-signaling receptor complex. In addition, it interacts with ST2/IL-1 R4 on mast cells and Th2 cells to create a functional IL-33 receptor complex. IL-1 RAcP also functions as a co-receptor for IL-36 alpha /IL-1F6, IL-36 beta /IL-1F8, and IL-36 gamma /IL-1F9.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q9NPH3
    
    Gene ID
    
    3556
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human IL-1 RAcP/IL-1 R3 (C-Fc-6His)

Recombinant Human IL-1 RAcP/IL-1 R3 (C-Fc-6His)

More Information

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