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Overview
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HSPB3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (1-150) and having a molecular mass of 19.1 kDa. The HSPB3 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. HSPB3 is a muscle-specific small heat shock protein which is expressed specially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) are highly expressed proteins with varied roles, including the assembly and impounding of multi-protein complexes, transportation of nascent polypeptide chains thru cellular membranes and regulation of protein folding. HSPB3 perform as an ATP-dependent chaperone protein which takes part in the refolding of denatured proteins and inhibition of actin polymerization.
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- Properties
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Overview