Recombinant Human Glutathione Synthetase/GSH Synthetase (C-6His)

Recombinant Human Glutathione Synthetase/GSH Synthetase (C-6His)

Catalog Number:
P001410790ABE
Mfr. No.:
Abe32-9416
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      • Overview
        • Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

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      • Properties
        • Protein Name
          Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS
          Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 200mM NaCl, pH 7.5 .

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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