Login / Register
0

Recombinant Human Flap Endonuclease 1/FEN-1

Recombinant Human Flap Endonuclease 1/FEN-1

Catalog Number:
P001415031ABE
Mfr. No.:
Abe32-7122
Price:
Inquiry
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • MW : 42.59kD. Recombinant Human Flap Endonuclease 1 is produced by our E.coli expression system and the target gene encoding Met1-Lys380 is expressed. Flap Endonuclease 1 (FEN1) is a member of the XPG/RAD2 endonuclease family. During DNA replication, FEN1 cleaves the 5-overhanging flap structure and processes the 5 ends of Okazaki fragments for synthesis. FEN1 also exhibits RNase H activity by possessing 5-3 exonuclease activity on gapped double-stranded or nicked DNA, FEN1 is involved in the long patch base excision repair (LP-BER) pathway, it can cleave within the apurinic/apyrimidinic (AP) site-terminated flap. FEN1 can prevent flaps from equilibrating into structures that lead to duplications and deletions. FEN1 is also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

          Please contact us at for specific academic pricing.

      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 50 mM Tris, 50mM NaCl, 1mM DDT, 10% Glycerol, pH 8.0.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          P39748
          Gene ID
          2237

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    We Also Recommend

    Recombinant Human GABA(A) Receptor-Associated Protein/GABARAP (N-GST)

    Recombinant Human GABA(A) Receptor-Associated Protein/GABARAP (N-GST)

    Recombinant Human Glutamate Oxaloacetate Transaminase 1/GOT1 (C-6His)

    Recombinant Human Glutamate Oxaloacetate Transaminase 1/GOT1 (C-6His)

    Recombinant Human Grancalcin/GCA (N-GST)

    Recombinant Human Grancalcin/GCA (N-GST)

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    Products
    Amerigo Scientific
    Support
    Contact Us
    Facebook Messenger Chat With Amerigo Scientific
    Copyright © Amerigo Scientific. All rights reserved.