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Recombinant Human DAPK1 (N-GST tag)

Recombinant Human DAPK1 (N-GST tag)

Catalog Number:

E001278283APP

Mfr. No.:

Z500099

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - Death-associated protein kinase 1 (DAPK1) is a positive mediator of apoptosis induced by ?-interferon. Activation of DAPK occurs via dephosphorylation of Ser-308 and subsequent association of calcium/calmodulin. DAPK is rapidly dephosphorylated in response to tumor necrosis factor or ceramide and then subsequently degraded via proteasome activity. The decline in DAPK expression is paralleled with increased caspase activity and cell apoptosis. Studies suggest that the apoptosis regulatory activities mediated by DAPK are controlled both by phosphorylation status and protein stability.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    DAPK, DKFZp781I035
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    71.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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