Recombinant Human D-Amino-Acid Oxidase/DAO (N-6His)

Recombinant Human D-Amino-Acid Oxidase/DAO (N-6His)

Catalog Number:
P001411031ABE
Mfr. No.:
Abe32-8087
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      • Overview
        • MW : 41.64kD. Recombinant Human D-Amino-Acid Oxidase is produced by our E.coli expression system and the target gene encoding Met1-Leu347 is expressed with a 6His tag at the N-terminus. D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, 1mM DTT, 2mM EDTA, pH 8.0 .
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          1610

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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