Recombinant Human CLK2 (N-GST tag)

Recombinant Human CLK2 (N-GST tag)

Catalog Number:
E001278289APP
Mfr. No.:
Z500093
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • CDC-like kinase 2 (CLK2) a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases) was shown to phosphorylate SR proteins and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the clk-2 proteins affect organismal features such as development, behavior, reproduction, and aging as well as cellular features such as the cell cycle, apoptosis, the DNA replication checkpoint, and telomere length.

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      • Properties
        • Name
          hCLK2, MGC61500
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          68.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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