Name: Recombinant Human Chymotrypsin-C/CTRC (C-6His)
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- Overview
  - MW : 29kD. Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus. Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q99895
    
    Gene ID
    
    11330
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Chymotrypsin-C/CTRC (C-6His)

Recombinant Human Chymotrypsin-C/CTRC (C-6His)

More Information

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