Recombinant Human CEACAM5/CD66e/CEA (C-Fc)

Recombinant Human CEACAM5/CD66e/CEA (C-Fc)

Catalog Number:
P001412554ABE
Mfr. No.:
Abe32-8780
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      • Overview
        • MW : 98.9kD. Recombinant Human CEACAM5 is produced by our Mammalian expression system and the target gene encoding Lys35-Ala685 is expressed with a Fc tag at the C-terminus. Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
          Storage
          Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          1048

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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