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Overview
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B-cell antigen receptor complex-associated protein beta chain (CD79B) is a single-pass type I membrane protein containing one Ig-like V-type (immunoglobulin-like) domain and one ITAM domain. CD79B is expressed on B cells and can form a covalent heterodimer with CD79A. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex. CD79B facilitates the phosphorylation of CD79A by recruiting kinases which phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.
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