Name: Recombinant human CCR5 protein with C-terminal human Fc tag
Price: Inquiry

- Overview
  - The protein has a predicted molecular mass of 38.83 kDa after removal of the signal peptide. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
    
    Source
    
    HEK293 cells
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
    
    Formulation
    
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    
    Storage
    
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant human CCR5 protein with C-terminal human Fc tag

Recombinant human CCR5 protein with C-terminal human Fc tag

We Also Recommend

Recombinant human CSF protein with C-terminal human Fc tag

Recombinant human CSF1 protein with C-terminal human Fc tag

Resistin Recombinant Protein