Recombinant Human Carbonic Anhydrase 8/CA8 (C-6His)

Recombinant Human Carbonic Anhydrase 8/CA8 (C-6His)

Catalog Number:
P001415011ABE
Mfr. No.:
Abe32-7097
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      • Overview
        • MW : 34.04kD. Recombinant Human Carbonic Anhydrase 8 is produced by our E.coli expression system and the target gene encoding Ala2-Gln290 is expressed with a 6His tag at the C-terminus. Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 500mM NaCl, 1mM DTT, pH 8.5 .
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
          Activity
          Specific Activity is greater than 56.08pmol/min/ug

          More Information

          UniProt
          Gene ID
          767

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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