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Recombinant Human c-MER (N-GST tag)

Recombinant Human c-MER (N-GST tag)

Catalog Number:
E001278236APP
Mfr. No.:
Z500047
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
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      • Overview

        • c-MER is a tyrosine kinase and a member of the MER/AXL/TYRO3 receptor kinase family. The c-MER gene encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. Functional knockout of c-MER in mice shows the mice to have macrophages deficient in the clearance of apoptotic thymocytes thereby demonstrating the critical role for c-MER in the engulfment and efficient clearance of apoptotic cells. Defects in c-MER have been associated with retinitis pigmentosa, a phenotype that can be reversed by replacement of the c-MER gene product.

          Please contact us at for specific academic pricing.

      • Properties
        • Name
          MER, MERTK, MGC133349
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          58.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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