Name: Recombinant Human Butyrophilin Subfamily 2 Member A1/BTN2A1 (C-6His)
Price: Inquiry

- Overview
  - MW : 25.4kD. Recombinant Human Butyrophilin Subfamily 2 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln29-Ala248 is expressed with a 6His tag at the C-terminus. Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisits of a 220 amino acid (aa) extracellular domain with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 258 aa cytoplasmic domain. Alternative splicing generates additional isoforms of human Butyrophilin 2A1 that lack the first Ig like domain or transmembrane segment as well as isoforms with substitutions and deletions in the cytoplasmic region. BTN2A1 is widely expressed including on colonic epithelial cells, on immune cells, and in milk fat globules. It binds to the C-type lectin DCSIGN on monocytederived dendritic cells, and this interaction can be blocked by soluble gp130 from HIV. The polymorphism of BTN2A1 has been associated with metabolic syndrome, type II diabetes mellitus, chronic kidney disease, and hypertension.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q7KYR7
    
    Gene ID
    
    11120
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Butyrophilin Subfamily 2 Member A1/BTN2A1 (C-6His)

Recombinant Human Butyrophilin Subfamily 2 Member A1/BTN2A1 (C-6His)

More Information

We Also Recommend

Recombinant Human Delta-like Protein 1/DLL1 (C-6His)

Recombinant Human Delta-like Protein 4/DLL4 (C-10His)

Recombinant Human Fibroblast Growth Factor 4/FGF-4