Name: Recombinant Human Delta-like Protein 1/DLL1 (C-6His)
Price: Inquiry

- Overview
  - MW : 57.3kD. Recombinant Human Delta-like Protein 1 is produced by our expression system and the target gene encoding Gln18-Gly540 is expressed Delta-like protein 1 (DLL1) is a type I transmembrane protein that belongs to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Mature human DLL1 consists of a 528 amino acid (aa) extracellular domain (ECD) with one DSL domain and eight EGF-like repeats, a 23 aa transmembrane segment, and a 155 aa cytoplasmic domain. Within the ECD, human DLL1 shares 91% aa sequence identity with mouse and rat DLL1. The residual membranebound portion of DLL1 can be cleave by presenilin-dependent gamma -secretase, enabling the cytoplasmic domain to migrate to the nucleus. DLL1 localizes to adherens junctions on neuronal processes through its association with the scaffolding protein MAGI1. DLL1 is widely expressed, and it plays an important role in embryonic somite formation, cochlear hair cell differentiation, plus B and T lymphocyte differentiation. The upregulation of DLL1 in arterial endothelial cells following injury or angiogenic stimulation is central to postnatal arteriogenesis. DLL1 is also overexpressed in cervical carcinoma and glioma and contributes to tumor progression.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    O00548
    
    Gene ID
    
    28514
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Delta-like Protein 1/DLL1 (C-6His)

Recombinant Human Delta-like Protein 1/DLL1 (C-6His)

More Information

We Also Recommend

Recombinant Human Delta-like Protein 4/DLL4 (C-10His)

Recombinant Human Fibroblast Growth Factor 4/FGF-4

Recombinant Mouse C-C motif chemokine 2/CCL2