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Recombinant human beta-Synuclein protein , 1-134aa

Recombinant human beta-Synuclein protein , 1-134aa

Catalog Number:
P001445754NKM
Mfr. No.:
SNB2001
Price:
$210
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      • Overview

        • Please contact us at for specific academic pricing.

      • Properties
        • Protein Name
          Beta-synuclein, SNCB beta-Synuclein, B-synuclein, Beta synuclein, beta synuclein, Phosphoneuroprotein 14, PNP14, Synuclein beta
          Type
          Recombinant Proteins
          Purification
          > 95% by SDS-PAGE
          Formulation
          Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl,1mM MgCl2
          Storage
          Stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
          Concentration
          1mg/ml (determined by BCA assay)
          Molecular Weight
          14.2 kDa (134aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
          Expression system
          E.coli

          More Information

          UniProt
          Q16143

          * For research use only. Not intended for human, diagnostics or veterinary use.

      • Applications
        • Application
          SDS-PAGE
      • Reference

        • Ahn KJ, et al. Amino acid sequence motifs and mechanistic features of the membrane translocation of alpha-synuclein. (J Neurochem. 2006)
          JY Park, et al. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease. (Glia. 2008)
          Konno M, et al. Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells. (J Biol Chem. 2010)
          Konno M, et al. Suppression of dynamin GTPase decreases a-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. (Mol Neurodegener. 2012)
          Førland MG, et al. Validation of a new assay for α-synuclein detection in cerebrospinal fluid. (Clin Chem Lab Med. 2017)
          Kobayashi J, et al. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis. (FASEB J. 2019)

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