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Overview
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Beta-defensin 4 is a member of beta-defensin family. Beta-defensins are expressed on some leukocytes and epithelial surfaces and are highly expressed in the testis. It plays an important role in the innate immune system. Four human Beta-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. The Beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence.
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