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Recombinant Human Autophagy Related 10 Homolog/ATG10 (C-6His, N-T7 tag)

Recombinant Human Autophagy Related 10 Homolog/ATG10 (C-6His, N-T7 tag)

Catalog Number:
P001411007ABE
Mfr. No.:
Abe32-8059
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      • Overview

        • MW : 24.5kD. Recombinant Human Autophagy protein 10 is produced by our E.coli expression system and the target gene encoding Met1-Thr190 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus. Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 8.0.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Q9H0Y0
          Gene ID
          83734

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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