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Recombinant Human Arginase-1/ARG1(C-6His)

Recombinant Human Arginase-1/ARG1(C-6His)

Catalog Number:
P001412605ABE
Mfr. No.:
Abe32-8835
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      • Overview

        • MW : 35.6kD. Recombinant Human Arginase-1 is produced by our Mammalian expression system and the target gene encoding Met1-Lys322 is expressed with a 6His tag at the C-terminus. ARG1 is a member of the ureohydrolase family of enzymes. ARG1 can catalyze the hydrolysis of arginine to ornithine and urea. In the urea cycle, ARG1 catalyzes the fifth and final step, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. ARG1 is a cytosolic enzyme and expressed widely in the liver as part of the urea cycle, while it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Inherited deficiency of this ARG1 causes argininemia, which is an autosomal recessive disorder characterized by hyperammonemia.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 10mM Tris-HCl, 1mM 2-mercaptoethanol, 2mM MnCl2, 150mM NaCl, pH7.5.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          P05089
          Gene ID
          383

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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