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Recombinant Human ALK3 (BMPR1A) (N-GST tag)

Recombinant Human ALK3 (BMPR1A) (N-GST tag)

Catalog Number:

E001278223APP

Mfr. No.:

Z500011

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - BMPR1A (also known as bone morphogenetic protein receptor 1A) is a member of the transmembrane serine/threonine kinase family that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A act as a minor susceptibility gene for PTEN-mutation-negative Cowden syndrome. BMPR1A regulates the PTEN protein levels by decreasing PTEN's association with the degradative pathway. BMPR1A trafficking plays a significant role in FOP pathogenesis and is also involved in human T-cell differentiation.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    ALK3; BMPR1A; 10q23del; ACVRLK3; CD292; SKR5
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    66.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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