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Overview
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AHA1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 320 amino acids (19-337) and having a molecular mass of 36.1 kDa. AHA1 is a cochaperone that stimulates hsp90 ATPase activity. AHSA1 binds the middle domain of Hsp90 (amino acid 272-627) and functions as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding. AHA1 affects a step in the endoplasmic reticulum to golgi trafficking.
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Overview