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Recombinant Human 5T4 Protein with C-terminal 6×His tag

Recombinant Human 5T4 Protein with C-terminal 6×His tag

Catalog Number:
P001417546ABE
Mfr. No.:
Abe32-17126
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      • Overview

        • The protein has a predicted molecular mass of 36.1 kDa after removal of the signal peptide. The apparent molecular mass of 5T4-His is approximately 55-70 kDa due to glycosylation. This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5 UTR results in multiple transcript variants that encode the same protein.

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      • Properties
        • Protein Name
          5T4; 5T4AG; M6P1; WAIF1
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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