Name: Recombinant Human 5'-Nucleotidase/5'-NT/CD73 (C-6His)
Price: Inquiry

- Overview
  - MW : 58.8kD. Recombinant Human 5-Nucleotidase is produced by our Mammalian expression system and the target gene encoding Trp27-Lys547 is expressed with a 6His tag at the C-terminus. CD73 is a glycosyl phosphatidylinositol (GPI) anchored membrane protein that belongs to the 5-nucleotidase family. CD73 is an ecto 5Nucleotidase expressed by most cell types. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 is a lymphocyte maturation marker that has functions independent of its catalytic activity. CD73 is also a regulator of leukocyte extravasation, a function that requires its 5Nucleotidase activity. Defects in NT5E are the cause of calcification of joints and arteries (CAJA). The recombinant CD73 lacking GPI anchor is secreted as a monomer.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 120mM NaCl, 4mM CaCl2, 20% Glycerol, pH 7.5.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P21589
    
    Gene ID
    
    4907
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human 5'-Nucleotidase/5'-NT/CD73 (C-6His)

Recombinant Human 5'-Nucleotidase/5'-NT/CD73 (C-6His)

More Information

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