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Recombinant Herpes Simplex Virus-1 gD

Recombinant Herpes Simplex Virus-1 gD

Catalog Number:
P001414511ABE
Mfr. No.:
Abe32-5391
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  • Size:
    0.5 mg
    Quantity:
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      • Overview

        • The E. Coli derived recombinant protein contains the HSV-1 gD immunodominant regions, 266-394 amino acids and fused to a GST-Tag at C-terminus. Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          HSV-1 gD protein is >95% pure as determined by 10% PAGE (coomassie staining).
          Formulation
          25mM Tris-HCl, 1mM EDTA, and 50% glycerol.
          Storage
          HSV-1 gD protein although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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