Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)

Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)

Catalog Number:
P001410800ABE
Mfr. No.:
Abe32-9383
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      • Overview
        • CD47(Integrin-Associated Protein,IAP) is a 40-60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

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      • Properties
        • Protein Name
          Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
          Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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