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Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

Catalog Number:
P001413026ABE
Mfr. No.:
Abe32-9326
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      • Overview

        • CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7, belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.

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      • Properties
        • Protein Name
          CD27 Antigen; CD27L Receptor; T-Cell Activation Antigen CD27; T14; Tumor Necrosis Factor Receptor Superfamily Member 7; CD27; CD27; TNFRSF7
          Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of 20mMTris, 150mM NaCl, pH8.5.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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