Recombinant Caspase 8 Monoclonal Antibody

Recombinant Caspase 8 Monoclonal Antibody

Catalog Number:
A001512053RED
Mfr. No.:
RD87013A
Price:
$392
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      • Overview
        • Calculated MW: 46kDa
          Observed MW: 46kDa

          Please contact us at for specific academic pricing.

          Background

          Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          hamster
          Immunogen
          A synthetic peptide of human Caspase-8
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          ALPS2B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, Apoptotic cysteine protease, Apoptotic protease Mch-5, Apoptotic protease Mch5, CAP4, CASP-8, CASP8, CASP8, Caspase 8, Caspase 8 apoptosis related cysteine peptidase, Caspase-8 subunit p10, CED 3, FADD Like ICE, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, FLJ17672, ICE-like apoptotic protease 5, MACH alpha 1/2/3 protein, MACH, MACH beta 1/2/3/4 protein, MCH5, MGC78473, MORT1 associated ced 3 homolog, MORT1-associated CED-3 homolog, OTTHUMP00000163717, OTTHUMP00000163720, OTTHUMP00000163724, OTTHUMP00000163725, OTTHUMP00000165062, OTTHUMP00000165063, OTTHUMP00000165064, OTTHUMP00000206552, OTTHUMP00000206582 (Gene ID:841; UniProt:Q14790)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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